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Pelvic inflammatory disease and sexually transmitted diseases, such as gonorrhea can also be quite common treated with quinolones. Anyone can get a kidney infection, but specific factors can increase the risk. Holding urine for amounts of time can also be a contributor. The inflammation invades the glomerulus (vascular bulb-like units inside the nephrons) and disturbs the kidney's capability to filter the blood for wastes. Microscopic variables include volume, pressure, and temperature.

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